This article presents the Structural Health Monitoring of the Central Tower at the Faculty of Physical and Mathematical Science of the University of Chile. The building has been monitored since 2009 with a network of 8 uniaxial accelerometers and 17 environmental sensors which register ambient conditions, like wind speed and direction, temperature, rainfall, ambient and soil humidity. The building is a nine stories, 30 meters high, shear wall reinforced concrete structure. During this period, it has been continuously monitoring ambient vibrations and more than 1700 seismic events of different intensity. Modal parameters are obtained automatically with frequency and time identification methods applied over ambient vibrations records. Earthquakes records are analyzed with multiple input multiple output (MIMO) techniques. Results of the analysis have been published automatically on Internet since the beginning of measurements. This article also presents an analysis of the seismic records on the building during the Mw=8.8 2010 Chile earthquake. Structural Damage was observed on the building and modal parameters changes were identified.