A study is made of the influence of the combined use of different types of manufacturing flexibility in conjunction with the use of inventory on the total flow time of batches in a production system. We propose 35 factorial experimental designs which consider labor flexibility, machine flexibility, routing flexibility, volume flexibility, and inventory, on three levels defined as high, medium and low. Their effects on the total flow time of the jobs in the manufacturing system were measured. The experiments were simulated using the Rockwell Arena software