The Chacao Bridge is the first major bridge project in Chile, and when built it will be the largest suspension bridge in South America. The 2,750 m-long structure will connect the island of Chiloé with mainland Chile across the Chacao Channel. The three-tower suspension bridge will have main spans over 1 km in length each. The design faces many challenges related to the environment where the bridge is located; high seismicity, high wind, volcanos, tsunamis, sea waves, and potential erosion of the central island (Roca Remolinos) and the shores. This paper presents the design and construction challenges for the project from the Owner's perspective. Also, it discusses the interaction within the project team: owner (MOP), owner's engineer (RyQ and COWI NA) and the construction JV working together for successful delivery of this high profile project.