Background and Objective. Primary tumor of the thoracic wall is a rare entity in children. Surgical treatment commonly involves resection of the chest wall, potentially leaving large defects that can require complex reconstruction. These may include skeletal and soft tissue reconstruction with al-loplastic materials and regional flaps. We report our experience in thoracic wall reconstruction after extensive resection due to primary wall tumors resection in children. Methods. We present 2 cases of pediatric patients with thoracic wall tumor who were managed multidisciplinary with wide resection and reconstructed with mesh coverage and latissimus dorsi myocutaneous flap. Results. The latissimus dorsi flap was a good alternative for coverage of skeletal reconstruction in the presented cases. Conclusions. Multidisciplinary management of these pathologies is fundamental given the need to perform large thoracic ablations.