Objective: To review the psichological effects of DM1 on children and adolescents, and review a clinical case. Method: SIBUC (Electronic System of PUC Lybrary) Bibliographic search. Clinical Case: 13 year old adolescent diagnosed with DM1 since the age of 3, with poor treatment adherence, and poor social relationships. History of Anxiety Disorders diagnosed at age 10, partially treated with medications and psychotherapy. Currently anxious, hopeless regarding illness outcome. Treated with Sertraline and psychotherapy, presented behavioral and autonomy issues. Review: The relationship between DM1 and psychiatric topics is reviewed, including some hypotheses, issues such as attachment, body-self relationship, separation-individuation. Suggestions are made for parents and treatment teams for systematic followup of these patients and in preventing and treating psychological complications of DM1. Conclusions: DM1 is associated to significant psychopathology in children and adolescents. Due to its complications, it needs to be prevented and treated promptly to improve the outcome of these patients.