Medicine in the world has changed, and Chile hasn't been left out of this reality. Advances in therapies for chronic diseases, neonatal intensive care, and critical care, have made children survive and improve infant mortality rates, with an increase in the number of children and adolescents with chronic illnesses and special health care needs. The special pediatric care of these patients has been developed in recent years, however, the transition to an adult health care model is a difficult experience for the patient, family and medical teams. The purpose of this document is to provide recommendations for the health personnel and authorities in Chile, to deliver an adequate and healthy transfer from the pediatric to the adult health care teams, which is called "Transition".