The objective of the present study was to analyze the prevalence of anemia and of iron deposits depletion (FeD) in pregnant adolescents from an urban (U) and rural (R) area. Methods: We studied 214 pregnant adolescents (U=100; R=114), from low socio-economic status. Clinical obstetric, nutritional situation and biochemical assessment was performed. Anemia in pregnant adolescents was determined during the first and third trimesters when Hh¡, 110g/L, second trimester Hb≤105g/L. FeD: ferritin <15µg/L; insufficient reserves of iron IRI=15-20µg/L and normal reserves of iron (RIN)>20µg/L, as recommended by WHO and the International Anemia Consultative Group. The statistical significance was considered when p<0.05. Results: The prevalence of anemia in pregnant adolescents with depleted reserves of iron (FeD+IRI) was 45.79% (R=22.90% vs U=22.89%); reserves of iron without anemia was 30.37%. (R=17.29% vs. U=13.08%); and anemia with RIN was 9.34% (R=6.07% vs. U=3.27%); there was a statistically significant association to urban (2=8.1282 p=0.0172) and rural area (2=11.6270p=0.0030). Conclusion: Iron deficiency anemia is a common complication in pregnant adolescents from rural and urban areas. This situation is associated with nutritional bad habits in adolescents. Strategies for recovery nutrition and education in primary health care and maternal health programs are needed.