Purpose: to determine which anthropometric variable (body mass index (BMI), waist circumference (WC) or waist-to-height ratio (W/Ht) has a better relationship with VO2peak in young physically inactive women from Concepción, Chile. Methods: 31 physically inactive women from Concepción, Chile (age 20.39±1.58 years; weight 59.20±7.84 Kg; height 1.60±0.05 m) were assessed in three stages: general Information collection, anthropometric measuring (weight, height, WC, W/Ht, and BMI), and aerobic capacity determination, using Bruce's protocol associated to ergospirometry. For statistical analysis, Pearson's correlation coefficient was used, with p<0.05. Results: there is an inverse and moderate relationship between BMI, WC, and W/Ht with VO2peak in young physically inactive women from Concepción. Chile. W/Ht shows a higher correlation (r=-0.57; p<0.01) than CC (r=-0.49; p<0.01) and IMC (r=-0.45; p=0.01). Conclusions: W/Ht shows a better relationship with VO2peak than WC and BMI in young physically inactive women from Concepción, resulting in the anthropometric variable that most precisely determines cardiometabolic risk.