The essential oils obtained from the dried and fresh leaves of Duguetia glabriuscula - (Annonaceae) were analyzed by GC/MS and compared. By employing the usual phytochemical workup, five aromadendrane sesquiterpenes were isolated from the essential oil obtained from fresh leaves: alloaromadendran-14beta-al, alloaromadendrene, (-)-ledol, viridiflorol, and (+)-spathulenol. Alloaromadendran-14beta-oic acid was also obtained, having been generated by the spontaneous oxidation of its corresponding aldehyde. Both essential oils displayed activity against Artemia salina