Three models for estimating the daily reference evapotranspiration ETo are evaluated in the agricultural zone of Chillán, Chile: Penman-Monteith FAO PMF, Prietsley-Taylor PT and Hargreaves-Samani HS. The daily ETo values estimated through these methodologies are compared with the daily values of ETo estimated from pan evaporation ETB data series obtainedfrom meteorological stations of the Universidad de Concepción Campus Chillán and INIA Quilamapu, both located within Chillán ’s city limits. The comparison and analysis were performed with data covering a span of 13 years (1996 - 2008). Results indicate that the HS method systemically underestimates ETo values, particularly during dry periods. Moreover, differences between the three methods quantified with Root Mean Squared Error RMSE and Relative Differences RD computed for different time periods (1, 3, 7 and 30 days) suggest that the PT method fits better the observations, being more adequate for the agricultural area of Chillán - weekly averages yield RMSE of 1.01 mm/day and RD of 32.8%.