This paper contextualizes the variants of the symbolism of the head in use among the Reche, which was the ethnic name for the original inhabitants of southern Chile until the eighteenth century, today named Mapuche. Information is provided in intracultural terms while exposing its transcultural background. We explore the 'semiotic constellations' associated with this symbolism. That is, we read series of meaning relationships that make sense to the practice of taking heads of enemies killed in war, the ritual of beheading the prisoners, the use of their skulls as trophies and ceremonial instruments, and the preservation or burial of the heads of relatives and brethren for the reproduction of the social group. The recurrence and persistence of these practices among Amerindian groups in the Southern Cone, as well as the systems of representations about them, show the symbolism of the head of the Reche Mapuche as part of a Pan-Andean and Amazonian cultural pattern. This means that a cotradition around this cultural pattern has developed in this macro region.