The 2010 Mw=8.8 Maule earthquake, which occurred in the subduction contact between the Nazca and the South American tectonic plates off the coast of Chile, represents an important opportunity to improve understanding of the distribution and controls for the generation of landslides triggered by large megathrust earthquakes in subduction zones. This paper provides the analysis of the comprehensive landslide inventory for the Maule earthquake between 32.5 degrees S and 38.5 degrees S. In total, 1226 landslides were mapped over a total area of c. 120,500km(2), dominantly disrupted slides. The total landslide volume is c. 10.6Mm(3). The events are unevenly distributed in the study area, the majority of landslides located in the Principal Andean Cordillera and a very constrained region near the coast on the Arauco Peninsula, forming landslide clusters. Statistical analysis of our database suggests that relief and lithology are the main geological factors controlling coseismic landslides, whilst the seismic factor with higher correlation with landslide occurrence is the ratio between peak horizontal and peak vertical ground accelerations. The results and comparison with other seismic events elsewhere suggest that the number of landslides generated by megathrust earthquakes is lower than events triggered by shallow crustal earthquakes by at least one or two orders of magnitude, which is very important to consider in future seismic landslide hazard analysis.