Background: Flexible ureteroscopy is an increasingly used diagnostic and therapeutic tool for the upper urinary tract. Aim: To report our experience with flexible ureteroscopy. Material and Methods: Analysis of 13 procedures performed to seven males and 6 women aged 30 to 72 years. Results: The indications for flexible ureteroscopy were urinary lithiasis in six patients, a filling defect found in a CAT scan in five, proximal displacement of a double J catheter in one patient and unilateral hematuria in one patient. Lithiasis was managed with extracorporeal lithotripsy using a Holmium laser. Biopsies were obtained from the sites with filling defects; the catheter was extracted using a Dormia basket. In the patient with hematuria, a hemangioma was found and managed with laser excision. No complications were registered. Conclusions: Flexible ureteroscopy is safe and effective.