Proton decay is usually discussed in the context of grand unified theories. However, as is well known, in the standard model effective theory proton decay appears in the form of higher-dimensional non-renormalizable operators. Here, we study systematically the one-loop decomposition of the d = 6 B + L violating operators. We exhaustively list the possible one-loop ultraviolet completions of these operators and discuss that, in general, two distinct classes of models appear. Models in the first class need an additional symmetry in order to avoid tree-level proton decay. These models necessarily contain a neutral particle, which could act as a dark matter candidate. For models in the second class the loop contribution dominates automatically over the tree-level proton decay, without the need for additional symmetries. We also discuss possible phenomenology of two example models, one from each class, and their possible connections to neutrino masses, LHC searches and dark matter.