Sexually transmitted infections (STIs) are one of the main causes of acute illness, infertility, long-term disability and death in the world(1). This report presents the preliminary epidemiological situation of STIs up to the year 2017 in Chile. Syphilis is the STI with the highest reporting rate, followed by HIV infection. In general terms, all STIs present a relative stabilization of their rates in the 2014 and 2015 periods, except for gonorrhea that shows an increase in these years, which focuses on the group of 15 to 24 years. In 2017, syphilis and HIV infection showed an increase in their rates in relation to 2016. In all these STIs the rate of men exceeds that of women and the most affected age group is 15 to 39 years. According to geographical distribution, the regions of Arica-Parinacota to Antofagasta, Metropolitana, Valparaiso, Los Lagos and Aysen, present the greatest risks.