It is well known that the principle of minimal coupling in quantum mechanics establishes a unique interaction form for a charged particle. By properly redefining the canonical commutation relations between (canonical) conjugate components of position and momentum of the particle, e.g., a pi-meson, we restate the Klein-Gordon equation for the Coulomb-like problem incorporating a generalized minimal electromagnetic replacement. The corresponding interaction keeps the 1/|q| dependence in both the scalar potential V(|q|) and the vector potential A(q)(|A(q)|similar to 1/|q|). This equation can be exactly solved in closed form. Thus, we present a novel relativistic quantum-mechanical model which can be further explored.