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Single-cell revolution unveils the mysteries of the regenerative mammalian digit tip
| Indexado |
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| DOI | 10.1016/J.YDBIO.2020.02.002 | ||||
| Año | 2020 | ||||
| Tipo | material editorial |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
Abstract
The digit tip is an exciting model for studying regeneration in mammals, but the precise mechanisms and the populations of cells involved in the formation and remodeling of the blastema remain unknown. In an exciting new work, Storer et al. take advantage of single-cell RNAseq combined with Pdgfra+ lineage-tracing to open the way into the enigmatic world of mammalian tissue regeneration.
| Ord. | Autor | Género | Institución - País |
|---|---|---|---|
| 1 | Riquelme-Guzman, Camilo | Hombre |
Tech Univ Dresden - Alemania
Center for Regenerative Therapies Dresden - Alemania TECHNISCHE UNIVERSITAT DRESDEN - Alemania |
| 2 | Contreras, Osvaldo | Hombre |
Victor Chang Cardiac Res Inst - Australia
Pontificia Universidad Católica de Chile - Chile Victor Chang Cardiac Research Institute - Australia |
| Fuente |
|---|
| CONICYT |
| Comisión Nacional de Investigación Científica y Tecnológica |
| Deutsche Forschungsgemeinschaft |
| DFG |
| Comisión Nacional de Investigación CientÃfica y Tecnológica |
| Technische Universität Dresden |
| Beca de Doctorado Nacional |
| DIGS-BB fellow award |
| Zentrum für Regenerative Therapien Dresden |
| Victor Chang Cardiac Research Institute |
| Agradecimiento |
|---|
| We are grateful to Dr. Tatiana Sandoval-Guzman (DFG-Center for Regenerative Therapies Dresden, Technische Universitat Dresden, Germany) and Dr. Richard P. Harvey (Victor Chang Cardiac Research Institute, Darlinghurst, Australia) for proofreading the manuscript. This work was supported by Beca de Doctorado Nacional, folio 21140378 from CONICYT to O.C; DIGS-BB fellow award and DFG to C.R-G. The funding agency had no role in the design of the study, data collection, analysis, decision to publish, or preparation of the manuscript. We apologize to our colleagues and authors whose work could not be cited or was cited indirectly, due to space restrictions. |
| We are grateful to Dr. Tatiana Sandoval-Guzmán (DFG-Center for Regenerative Therapies Dresden, Technische Universität Dresden, Germany) and Dr. Richard P. Harvey (Victor Chang Cardiac Research Institute, Darlinghurst, Australia) for proofreading the manuscript. This work was supported by Beca de Doctorado Nacional, folio 21140378 from CONICYT to O.C; DIGS-BB fellow award and DFG to C.R-G. The funding agency had no role in the design of the study, data collection, analysis, decision to publish, or preparation of the manuscript. We apologize to our colleagues and authors whose work could not be cited or was cited indirectly, due to space restrictions. |
