We review bibliography on genus Diplodon (Spix, 1827) (Hyriidae) records obtained in archaeological contexts in Chile. Evidence indicates an ephemeral late Pleistocene presence of these bivalves, while its record increases significantly during the Holocene. Nevertheless, only few archaeological sites show its use as raw material and/or food resource. Diplodon archaeological evidence is similar to Current genus distribution. We discuss some palaeoenvironmental and biogeographical implications of their distribution, as well as the need to relate this information with different disciplines in order to understand its importance in archaeological contexts.