This paper describes the hourly simulation and optimization of a thermally driven cooling cycle assisted by solar energy. The double stage solar ejector cooling cycle is modelled using the TRNSYS-EES simulation tool and the typical meteorological year file containing the weather data of Florianopolis, Brazil. The first stage is performed by a mechanical compression system with R134a as the working fluid, while the second stage is performed by a thermally driven ejector cycle with R141b. Flat plate collectors and an auxiliary energy burner provide heat to the ejector cycle. The thermo-economical optimization is carried out with respect to the intercooler temperature and the flat plate solar collector area, for given specific costs of the auxiliary energy and electric energy, the capital cost of the collectors, ejector cooler, and the capital cost of equivalent mechanical compression cooler. (C) 2009 Elsevier Ltd. All rights reserved.