The present text offers a summary of some of the crucial food security problems in Latin American (LA) countries. This region, like many others in the globe, confronts such as food safety difficulties. The summary offers also an analysis of some technologically based solutions for LA food security issues. As a general call, the present review article calls for a collaborative and transdisciplinary approach to think deeper about how to solve food security problems, putting the focus on enabling technologies within a context of social, market, and global trends to achieve food and nutritional security. The review is positioned far from techno-optimisms and, at the same time, away from purely economic-based solutions. Conversely, this review embraces the whole complexity that brings economy-nature-technology triad. Embracing such complex relationships between technology, nature and the socio-economy aspects of food security LA issues. Such complexity also triggers a need for a solution that considers a renewed approach to sustainability in the whole food value chain from production to consumption. Sustainability in the value chain opens up a much-needed approach to LA food security that broadens, and refresh, our understanding of this fundamental socio-economic and technical phenomena.