Solid pseudopapillary pancreatic neoplasms (SPPN) are rare entities mainly diagnosed in young women. Prognosis is generally relatively favorable. Histological evaluation usually reveals papillary as well as solid areas of low malignant potential, as the name implies. A retrospective review of five cases, diagnosed and treated in our institution, is presented with the corresponding clinical and pathological data and follow-up. All SPPN occurred in women, with an average age of 19 years (13 to 27 years), who consulted for abdominal pain. In all patients, the tumors were > 4 cnn, distributed in several pancreatic segments. The histopathologic report confirmed papillary as well solid areas and low mitotic count. In two patients, neural and angioinvasion were found. (C) 2010 Elsevier Espana, S.L. All rights reserved.