We present South Pole Telescope (SPT) observations of the five galaxy cluster candidates in the southern hemisphere which were reported as unconfirmed in the Planck Early Sunyaev-Zel'dovich (ESZ) sample. One cluster candidate, PLCKESZ G255.62-46.16, is located in the 2500 deg(2) SPT SZ survey region and was reported previously as SPT-CL J0411-4819. For the remaining four candidates, which are located outside of the SPT SZ survey region, we performed short, dedicated SPT observations. Each of these four candidates was strongly detected in maps made from these observations, with signal-to-noise ratios ranging from 6.3 to 13.8. We have observed these four candidates on theMagellan-Baade telescope and used these data to estimate cluster redshifts from the red sequence. Resulting redshifts range from 0.24 to 0.46. We report measurements of Y-0'.75, the integrated Comptonization within a 0'.75 radius, for all five candidates. We also report X-ray luminosities calculated from ROSAT All-Sky Survey catalog counts, as well as optical and improved SZ coordinates for each candidate. The combination of SPT SZ measurements, optical red-sequence measurements, and X-ray luminosity estimates demonstrates that these five Planck ESZ cluster candidates do indeed correspond to real galaxy clusters with redshifts and observable properties consistent with the rest of the ESZ sample.